IMPACT OF SOLVENT TYPES ON ANTIMICROBIAL ACTIVITIES OF ROOT EXTRACT OF CAESARIA TOMENTOSA
By: Angle, Gauri Pai
.
Contributor(s): Sardessai, Yogita.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2019Edition: Vol.11(4).Description: 33-38p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
International journal of pharmacy and pharmaceutical scienceSummary: Objective:
The study deals with the antimicrobial activity of
five solvent extracts of roots of
Caesaria tomentosa
against seven microorganisms: two
gram-positive (
Staphylococcus aureus
and
Bacillus subtilis), three
gram-negative bacteria (
Escherichia coli, Pseudomonas aeruginosa
and
Salmonella
typhimrium)
and two fungal strains
(Candida albicans
and
Aspergillus niger).
Methods:
Roots of
C. tomentosa
were extracted with different solvents(n-hexane, et
hanol, chloroform, acetone and water) and were subj
ected to
antibacterial as well as antifungal screening by We
ll Diffusion Method. The Minimum Inhibitory Concent
ration(MIC) was also performed by two-fold dilution
.
Results:
The maximum inhibition zone at 50μg/ml concentratio
n of n-hexane was 32 mm. These indicate that some a
ctive substances in
C.
tomentosa
dissolved in varying degrees in the five solvents.
The MIC for n-hexane was 1.6 μg/ml for
S. aureus
leading to a conclusion that the n-
hexane extract was found to be the most potent.
Conclusion:
All extracts were very effective against
S. aureus.
As for the solvents, the n-hexane extract had the
best inhibitory effect among five
solvents tested.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2020905 |
Objective:
The study deals with the antimicrobial activity of
five solvent extracts of roots of
Caesaria tomentosa
against seven microorganisms: two
gram-positive (
Staphylococcus aureus
and
Bacillus subtilis), three
gram-negative bacteria (
Escherichia coli, Pseudomonas aeruginosa
and
Salmonella
typhimrium)
and two fungal strains
(Candida albicans
and
Aspergillus niger).
Methods:
Roots of
C. tomentosa
were extracted with different solvents(n-hexane, et
hanol, chloroform, acetone and water) and were subj
ected to
antibacterial as well as antifungal screening by We
ll Diffusion Method. The Minimum Inhibitory Concent
ration(MIC) was also performed by two-fold dilution
.
Results:
The maximum inhibition zone at 50μg/ml concentratio
n of n-hexane was 32 mm. These indicate that some a
ctive substances in
C.
tomentosa
dissolved in varying degrees in the five solvents.
The MIC for n-hexane was 1.6 μg/ml for
S. aureus
leading to a conclusion that the n-
hexane extract was found to be the most potent.
Conclusion:
All extracts were very effective against
S. aureus.
As for the solvents, the n-hexane extract had the
best inhibitory effect among five
solvents tested.
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